Serum amyloid P component binding to Shiga toxin 2 requires both a subunit and B pentamer.
نویسندگان
چکیده
Solid-phase binding, competitive binding, and cytotoxicity neutralization assays indicate that the B pentamer and A subunit both contribute to human serum amyloid P (HuSAP) component binding to Stx2. A polyvalent globotriaosyl-ceramide receptor analog, Daisy, did not competitively inhibit HuSAP binding, implying that the two ligands bind to different Stx2 domains.
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عنوان ژورنال:
- Infection and immunity
دوره 71 10 شماره
صفحات -
تاریخ انتشار 2003